Saturday , April 17 2021

This is what LSD does in your brain

Lysergic acid diethylamide, better known as LSD, is this psychedelic drug that causes hallucinations and what psychiatrists call "an altered state of consciousness." We have seen represented countless times as a whirlwind of colors that dissolve in pupils who consume it. But scientists have always had a doubt: How does LSD work?

Since the drug was discovered in 1983, little else has been able to find out exactly what it is in our brain. Recently, a team at the Zurich University Psychiatric Hospital has asked for The way in which our gray matter reacts to the LSD and have given an apparently precise hypothesis to explain the processes occur when taking a dose of LSD.

In his study, published on Monday in the magazine PNAS, The researchers provided LSD to 25 volunteers. Additionally, some of them were given ketanserin, a drug that blocks serotonin receptors, a neurotransmitter that has been thought to play an essential role in the travel experience that L & # 39; LSD. And they corroborated it: the subjects who took the acid and the ketanserin They did not experience the trip effects.

In addition, the scanners that analyzed the reaction of their brains to the drugs, detected that the LSD interrupted a main circuit between four parts of the brain, including the thalamus, that acts like a filter of information. Imagine: the brain full of freeways and the thalamus is a great customs that filters the information to process. The action of the LSD In all this it would be to dynamite the customs and allow the entrance of A much higher flow of information to the other parts of the brain.

Scientists announce that this deeper understanding of the functioning of the LSD can help solve the enigmas that the psychological disorders such as depression or schizophrenia, in which the brain produces, for itself, effects similar to those of the drug.

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