Fulham fired manager Slavisa Jokanovic and replaced him with Claudio Ranieri, who led Leicester in the title of the Premier League in 2016.
Jokanovic got up with Cottagers who were sitting at the bottom of the table in the Premier League with five points from 12 matches.
Italian Ranieri, 67, received a "multi-year" contract by the Londoners.
"Making changes without a real response or a succession plan was not an option," President Fulham Shahid Khan said.
"So someone who is in the Claudius' caliber ready to accept our challenge was comforting but, above all, necessary.
"Claudio is without risk and ready for the Premier League, and especially because of what we need at this moment in Fulham.
"His recent collaboration with Leicester Citi is literally legendary, and then you look at Claudius' experience with Chelsea and big clubs all over Europe, and it's obvious that we are waiting for an extraordinary footballer in the Fulham Football Club."
Khan said that he and his son, Tony Khan, vice president and director of football operations, talked with many potential candidates during the past week.
"I am honored to accept Mr Kan's invitation and the opportunity to lead Fulham, a fantastic club with a tradition and history," said Ranieri, who spent last season in charge of the French club Nantes.
"The goal in Fulham should never be to survive in the Premier League, but we must always be a hard opponent and we should expect to succeed.
"This team Fulham has an extraordinary talent that is contrary to his position on the table."
Ranieri's first game will be in charge of seeing Fulham host Southampton at Craven Cottage on Saturday, November 24th.
"I know that this team is very capable for better performance, which we will be working on as soon as we prepare for Southampton in the hut," he added.
Ranieri Roller – the title of the shock for the sack
Despite great experience with clubs such as Valencia, Juventus, Inter Milan, Roma and Monaco, Ranieri joined Leicester City in 2015 to cast an unsuccessful manuscript as the head of Greece, including losses on the European Minnesota Faroe Islands during qualifying for the Euro 2016.
The Italian earned the nickname "Tinkerman" during his previous season in England who was in charge of Chelsea, where he led Blues for the other in the Premier League, as well as scored the semifinals of the Champions League.
More than a decade later, his Leicester side started the 2015-16 season. Years like 5,000-1-1 outsiders to win the Premier League and were among the favorites for the relegation.
However, Fokes provided one of the biggest sporting shocks of all time, as they entered the first English title of the first flight, which many described as "a miracle."
Fairy could not continue, however, Ranieri dismissed the next campaign – only nine months after he issued the title.
Jokanovic dismisses "correct decision"
Jokanovic, who joined the club in December 2015, drove Fulham to the promotion through the upcoming season.
But so far, they registered only one win on their return to the Premier League after four seasons in the championship.
"I did not expect to have to publish this statement regarding Slavisa and I wish that the circumstances were such that I did not have to, but our time in this season brought me what I know the exact solution at the right time, for our players, the club and our fans" , added Khan.
"Slavisa will always respect and appreciate everything he has done to bring Fulham back to the top flight team.
"I hope that everyone in the Fulham family shares my heart for Slavs and join me so I want success and happiness, no matter where the next station is."