Monday , May 16 2022

Scientists have discovered a sign of cancer



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Photo: Pikabai

Scientists at the University of California at Los Angeles have discovered a mechanism that allows cancer cells to cheat glucose and obtain the energy needed for survival and tumor growth, reports MedicalKspress. However, the content of certain molecules, on the basis of which the pre-cancerogenic state can be determined, is increased in the cells, reports BTA.

The scientists identified a molecule known as sodium glucose cotransporter 2 (SGLT2). It is a protein that is responsible for the transmission of glucose into the cell's interior. Cancer cells need glucose to ensure their survival and growth. Because of this, another type of transport protein, known as glucose transporters (GLUT), is extremely important to them. Previous studies have shown that SGLT2 can play an important role in the development of some cancers, including prostate and pancreas.

Positron emission tomography is now used to determine the activity of various glucose transporter in lung cancer cells at certain stages of the disease. It turned out that a large amount of SGLT2 is contained in these cells. This suggests that the newly opened tumor is delivered with carbohydrates, mainly via sodium glucose cotransporter instead of GLUT. In addition, the increased concentration of SGLT2 may be present before the onset of the tumor. This converts the respective sodium glucose co-transporter into an effective marker for the detection of malignant tumor formations at an early stage in their development.

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