Tuesday , May 17 2022

Can vaccines prevent, or even treat, a long covid?


It is estimated that between 10% and 30% of patients with Covid-19 develop long Covid, where symptoms last for months after an initial coronavirus infection, but recent research suggests that Covid-19 vaccines may help prevent and relieve these symptoms in the long term.

Initial research on long-term prevention of Covid

Some early research has found that Covid-19 vaccines help prevent and relieve long-term Covid symptoms. A published study The Lancet in September it was found that fully vaccinated people were 49% less likely to have long-term symptoms of Covid than those who were not vaccinated.

“I think this is the first study to show that long Covid is reduced by double vaccination and is significantly reduced,” said Claire Steves, geriatrics and clinical scholar of King’s College in London, who was the lead author of the study.

And those who were vaccinated and developed Covid for a long time experienced symptoms less often than unvaccinated people with the disease, according to the study.

“We haven’t had a Covid treatment in a long time,” Steves said. But getting vaccinated “is a prevention strategy in which everyone can participate,” he said

Another small UK preliminary study found that the long-term Covid symptoms of 44 vaccinated patients improved slightly compared to 22 long unvaccinated long-term Covid patients.

Does post-infection vaccination reduce the long-term symptoms of Covid?

But recently one of the most important studies was published on whether Covid-19 vaccines can relieve symptoms after people have already developed Covid for a long time. The Lancetprepress server.

The French study examined 455 vaccinated and 455 unvaccinated long-term Covid patients and found that the remission rate among vaccinated patients was 16.6% four months after vaccination, compared with 7.5% of those vaccinated. unvaccinated patients.

Vaccinated patients also reported an average of 13 symptoms four months after vaccination, compared with 15 previous symptoms, and vaccinated patients reported that their long Covid had a lower impact on their lives than unvaccinated patients. .

Viet-Thi Tran, associate professor of epidemiology a University of Paris and the lead author of the study, said he believes Covid-19 vaccines can remove a virus deposit in the body that could be causing long Covid. However, Tran added that it is possible that the placebo effect may be a factor, as patients may feel better after being vaccinated because they wait.

Akiko Iwasaki, professor of immunobiology a Yale University, said the study’s findings are consistent with the hypothesis that Covid-19 vaccines can remove the virus left over from the body that could cause symptoms.

The findings also suggest that long Covid could be caused by an autoimmune system reaction, Iwasaki said, meaning that vaccination can temporarily stop the secretion of toxic cytokines, which can relieve symptoms.

David Putrino, director of innovation in rehabilitation of Mount Sinai Health System, said he has more than 400 long-term Covid patients in a rehabilitation program and that about half have reported that their condition has improved after vaccination, while the other half feel the same or worse.

Putrino said he considers the French study’s findings that “the vaccine modulates symptoms” to be “convincing,” but added that he considers it important to find out why some patients feel better while others do not.

Daniel Griffin, head of the infectious diseases division for ProHealth NY, said approximately 60% of long-term Covid patients on the network have reported that their conditions have improved after being vaccinated.

“What we normally see is an improvement, but not a complete recovery,” Griffin said. “So now I can smell it again. Now I can go back up that flight of stairs. I can go back to work, but I still have to go to sleep when I get home.” (Reddy, Wall Street Journal, 10/11; Scully, The hill, 9/2)

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