A new study linked adolescent obesity to up to four times the risk of pancreatic cancer later in life. The results of the study also suggest that overweight and even higher weight in the "normal" weight range in men may increase the risk of pancreas in a graded manner. Findings are published early online CANCER, a revised magazine American Cancer Société.
Pancreatic cancer is the sixth most common cause of cancer-related deaths worldwide, and studies have linked obesity to adults with an increased risk of developing it. For the detection of any potential adolescent association, Zohar Levi, MD, Rabin Medical Center and University of Tel Aviv and his colleagues analyzed 1,087,358 Israeli Jewish men and 707,212 Jewish women who underwent a mandatory physical examination of ages 16 to 19 from 1967 to 2002. The frequency of pancreatic cancer by 2012 was identified by linking with the Israeli National Cancer Register.
Through a median of 23.3 years of follow-up, 551 cases of cases of pancreatic cancer have been identified, including 423 cancer in men and 128 cancer in women. Compared to normal weight (5th to <85th percentile), obesity (95th percentile) is associated with a risk of 3.67 times in males and a 4.07 times higher risk for women.
Among men, high normal BMI (? 75 to <85. Percentile) and overweight (85 to <95. Percentile) were associated with a 49 percent and 97 percent higher risk of cancer compared to low normal BMI (? 25. percentil).
"The total population of the attributed part of pancreatic cancer due to adolescent overweight and obesity was 11 percent among this Jewish Jewish population," said Dr. Left.
The assistant editor of the Maianei Haieshua Medical Center in Israel, Chanan Meidan, emphasizes systemic inflammation caused by obesity as a potential driver behind the development of pancreatic cancer.
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