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How artificial intelligence can determine what tumors can return to cancer | Technology and science | Sciences


The use of the artificial intelligence to improve the diagnosis of cancer and other evils continues its advance. In the last year, research on breast and lung cancer has shown promising advances in this regard.

Now a new study has shown that a laboratory test that uses artificial intelligence tools has potential for To determine with more precision what people with pancreatic cysts They will develop into a future pancreatic cancer.

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The description of the tool, for now a proof of concept, is published in the journal Science Traslational Medicine and according to its managers, although the results are "Exciting, it needs to be validated prospectively."

called "CompCyst"(In English, for the complete analysis of cysts), this test incorporates molecular and clinical markers of the cyst fluid and" seems to be in the path ofand significantly improve clinical and conventional image testing", Johns Hopkins Medicine points out in a note.

The test was developed based on data from patients, including those related to patients Symptoms, images of computed tomography and molecular characteristics As alterations of the DNA within the cyst fluid.

Thus, the molecular profiles of a large number of were evaluated pancreatic cysts (862), to whom clinical and radiological information was added in a program that used the artificial intelligence to classify patients in three different groups.

Those with cysts without potential to return tumors and for those who would not require periodic monitoring; cysts that have a small risk of progressing to cancer and for which patients must receive periodic monitoring; and cysts for which surgery is recommended for the high probability of progression to cancer.

Scientists found that surgery was not necessary in 45% of cases: this unnecessary surgery was performed because the doctors could not determine if the cysts were dangerous.

If you had used it CompCyst, From 60 to 74% of patients – depending on the type of cyst- They could have been saved from unnecessary surgery, According to the same sources.

the pancreatic cysts -Sucks of liquid in the pancreas- are common; They are in 4% of the people in the 60s and in 8% of the majors of 70. About 800,000 people with pancreatic cyst They are identified every year only in the US, although, according to the researchers, only a small part of these develops cancer.

Although most of these cysts are not cancerous, the dilemma faced by patients and doctors is the ability to distinguish between those who are precancerosos and cysts that will not progress to the tumor, says Anne Marie Lennon, one of the authors of this work and a doctor at the Johns Hopkins Kimmel Oncology Center.

Clinical and current clinical trials "often" do not do so, which makes it difficult to determine which patients will not require follow-up, which ones they will need in the long term and which patients should apply immediate removal surgery.

For this reason, Christopher Wolfgang adds, practically to all the people who are diagnosed with pancreatic cyst It's a long-term follow-up and surgeons have to make risk-benefit recommendations with limited information.

"We rarely lose one cancerBut it is at the expense of carrying out an operation that may not have been necessary afterwards, "notes Wolfgang, who summarizes: this study directly addresses these fundamental problems in the management of these cysts.

Source: EFE / El Comercio

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