Pancreatic cancer is more deadly in overweight patients before 50 years, suggest new research.
Scientists from the American Cancer Society discovered that a BMI of 30 or more increases the risks of pancreatic cancer killing a patient by 25 percent.
Current theories suggest that inflammation that comes with excess weight can encourage cells to mutate and become cancerous.
Pancreatic cancer has increased in recent years: it struck Alex Trebek and claimed the life of Aretha Franklin: disconcerting doctors as the main risk factor, which they smoke, diminish, but the new study suggests that the Obesity can be the fault.
New research suggests that panther cancer is 25 percent more deadly for people who gain weight before 50 years and that the first people get rid of pounds, the worse is their likelihood
Pancreatic cancer is still considered a rare form, but rates have increased in recent years.
"We have been baffled by this increase, since smoking, an important risk factor for pancreatic cancer, is declining," says Dr. Eric Jacobs, scientific director of the American Cancer Society and co-author of the new study.
Although the pancreas is one of the most ill-considered forms of cancer, smoking is an important and important risk factor.
However, pancreatic cancer rates have continued to increase although smoking has reached a record low in the US, leaving the scientists perplexed and looking for some other change that could be driving the trend.
Now, scientists may have found a possible explanation: the obesity epidemic.
Excess body weight is a major risk factor for all types of illnesses, including six forms of cancer: uterine, esophagus, stomach, kidney, liver, certain brain tumors, pancreatic and colorectal cancers, and multiple myeloma.
The research also suggests that overweight can make these cancers more deadly and, even if these people survive cancer, they will probably have a poorer quality of life.
People with overweight or obesity have up to 150 percent more likely to develop pancreatic cancer at some point in their lives than those who have a normal weight.
But obesity is not believed to be a cause of cancer, but a risk factor.
Smoking, on the other hand, has directly accused one-quarter of the cases of pancreatic cancer.
And, however, since the number of Americans that smoke has dropped 65 percent since 1965, the pancreatic cancer rate has increased 17.4 percent since 1999.
The new study suggests that the tendency of the country towards obesity could suppose the discrepancy.
"It is likely that the weight gain of the US population is a suspect, but previous studies have indicated that excess weight is only related to a relatively small increase in risk, which does not seem large enough to explain the Recent increases in pancreatic cancer rates. " Dr. Jacobs.
But his new study changes that, watching over weight, people gain when they are younger.
Dr. Jacobs and his team analyzed data on 963,317 people without a history of cancer, starting in 1982 to see if those who were overweight before 50 years would have higher probabilities of developing pancreatic cancer.
Between 2014 and 2014, 8,354 of the group died of pancreatic cancer.
And those who were overweight before life were more likely to be among the dead, even if they were not deadly.
For example, a 5 person who had been overweight at 32 pounds between the ages of 30 and 49 had a 25 percent greater risk of dying from pancreatic cancer than someone who had a healthy weight at that age
If this same person was prima before the 50, but it got to exceed 32 pounds between the ages of 50 and 59 years, its risk of death increased by 19 percent and 14 percent for those who were overweight among the 60 and 69 years old.
Thus, the sooner he won his life, someone would increase the risks of dying because of the illness that was difficult to capture.
Based on these results, Dr. Jacobs estimated that overweight will be the driving force of 28% of pancreatic cancer deaths for people born between 1970 and 1974.
On the contrary, it estimates that only 15 of the pancreatic deaths of people born in the 1930s, when obesity was much less common.
Overweight already increases the risk of a person developing cancer in general – and, in particular, pancreatic cancer – about 20 percent, so that the results of the new study show the critical importance of # 39; a healthy weight, especially before life.
"Our results suggest that to stop and, finally, reverse the last increases in pancreatic cancer rates, we will have to do better to prevent weight gain in young children and adults, an achievement that would also help prevent many others illnesses, "said Dr. Jacobs. finger